Senior Mechanical Engineer
Opto Biosystems
San Francisco, CA, USA
Posted on Apr 28, 2026
Job Title: Senior Mechanical Engineer, Product Development
Location: San Francisco
Type: Full-Time (on-site)
Coherence Neuro is a fast-growing, venture-backed company pioneering implantable technologies that interface with the human body to address critical unmet medical needs. We're looking for driven individuals who are passionate about pushing the boundaries of engineering and science to solve some of the most complex biological challenges. In this early-stage environment, we seek versatile team members with a hands-on approach and a willingness to learn quickly and adapt. We value diversity and encourage applicants from all backgrounds to join us in our mission. Learn about our team here!
Role Overview
We are seeking a Senior Mechanical Engineer in the Product Development group to lead the design and development of next-generation implantable medical devices. This role will focus on mechanical architecture, system integration, and product realization—from early concept through first-in-human readiness.
You will play a key role in shaping product design, driving technical decisions, and mentoring junior engineers
Key Responsibilities
Lead mechanical design and development of implantable medical devices and supporting external hardware
Own product architecture, including materials selection, packaging, and structural design
Translate system requirements into robust engineering solutions and design specifications
Plan and execute verification and validation activities (DVT, reliability, environmental testing)
Drive design for manufacturability (DFM) and support transfer to manufacturing
Collaborate cross-functionally with electrical, firmware, clinical, regulatory, and quality teams
Manage external partners (CMs, suppliers, test labs) to ensure design intent and timelines are met
Provide technical leadership and mentorship to junior engineers.
Required Qualifications and Skills
Please ensure the minimum requirements are evident on your resume.
Bachelor’s degree in Mechanical Engineering, Materials Science, or related field (advanced degree preferred)
5+ years of industry experience developing Class III active implantable medical devices from concept through first-in-human
Strong proficiency in CAD (e.g., SolidWorks, Creo)
Experience with implantable materials, hermetic or semi-hermetic packaging, and biocompatibility considerations
Demonstrated experience with manufacturing processes (e.g., machining, microfabrication, laser welding, molding, assembly)
Experience working with contract manufacturers and external development partners.
Solid understanding of design controls, risk management (FMEA), and regulated product development
Bonus Skills
Experience with neurostimulation or implantable electronic systems
Familiarity with hermetic sealing approaches (ceramic, titanium, glass)
Experience with flexible circuits, thin-film technologies, or microfabrication
Strong understanding of GD&T and tolerance stack analysis
Experience in early-stage or startup environments
Hands-on prototyping and lab testing experience
Reporting Structure:
This role is an integral part of the product team and reports directly to the VP of Engineering.
Benefits:
US standard
Healthcare, dental and vision
401k with company match
Industry leading paid time off (PTO) - 20days/year + holidays
Meals and snacks provided
Professional development support and training opportunities.
Flexible working hours and travel opportunities (We have sites in Australia, UK and US!)
A chance to work on impactful, life-changing technologies in a dynamic, innovative environment.
If you are passionate about innovation in healthcare, we would love to hear from you! Please submit your application here.
